The star has donated the complete sum of his £25k honor prize money to the trust for venues, which functions to preserve the United Kingdom's grassroots live music spots.
The star was awarded the cheque on October 16 as his latest record his work was declared the top album of the past year.
Fender has decided to hand the money over to the MVT, in recognition of the vital role grassroots venues had in his beginning days.
"I would not have achieved my current career if it hadn't been for all the shows I did around the area, and further afield, when I was beginning," said Sam Fender. "These venues are iconic, but they are facing challenges."
Since the start of 2023, more than 150 of these locations have ceased operations – roughly one-sixth of the whole industry in the UK.
Over the past year, well-known musicians including Pulp, Coldplay, Katy Perry and Ed Sheeran have all supported the MVT in its efforts to support the industry, by including a small levy to their admission fees, which supports independent venues.
He also took part, collecting in excess of £100,000 on his live tour to help 38 small stages across Britain.
These funds helped spaces that were dealing with potential shutdown due to issues caused by flooding, blazes and bereavements, as well as permit problems, legal disputes and sound issues.
Additional spaces obtained monetary aid in modernizing infrastructure and sound and lighting systems that helped musicians and concertgoers.
"The notion that funds from shows in major spaces backs the local stages, where it begins for musicians like me, is just sensible," Sam Fender has said.
The musician is among several artists to donate his Mercury Prize winnings to worthy causes.
When they won the award in the mid-90s for their release Different Class, lead singer Jarvis Cocker declared that the act would donate their prize money to the non-profit the charity.
During 2002, rapper and singer she split her prize across multiple organizations, like the children's charity and a Sickle Cell charity.
"And I contributed a thousand pounds to my local community centre, to their gymnastics program, because I practiced gymnastics when I was growing up and they lacked new equipment," she told a publication.
Two years ago, the band gave their funds to the community center that developed their band, as well as other independent music bodies.
Also the 1994 recipients M People contributed their award to a multiple sclerosis charity after a acquaintance was found to have the condition.
"Receiving the award was quite enough," said artist Small. "The cash was the extra but we could do without the cherry, because we had the cake. So our winning affected another person's life."
Last week, the MVT shared it had saved several local spots in south-east England, by transferring them to community ownership.
The first in that area and The Croft in Bristol were acquired under the Own Our Venues program, which is backed by a national body and music fans who purchase "ownership units" in the buildings.
